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Moreover, nicotine exposure from non-cigarette products was not examined here, and the directionality between smoking and depression cannot be fully disentangled given evidence that depression may influence smoking behavior [16]

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Another factor in decreased birth weight is fetal growth restriction, which occurs because nicotine constricts uterine blood vessels, thus reducing the amount of blood flow to the fetus, and also adds the oxygen blocker carbon monoxide to the blood flow, which decreases the amount of oxygen available to the baby