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Only 51% of all the studies [62% of the 11 outcomes ( n = 59)] reported on health effects associated with daily e-cigarette users

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In a statement to Reuters, the FDA said data in 2020 showed teens "overwhelmingly preferred" cartridge e-cigarettes like Juul, and that the agency "has the ability to shift enforcement priorities based on new data and information." The bigger problem for the FDA: Its approval process is considered so onerous that many e-cigarette manufacturers just skip it, even though sweet flavors remain potentially legal in disposable vapes

Isotretinoin induced psychotic mania: a case report