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The focus was on coding variants that could alter the protein sequence, such as protein-truncating variants (i.e., nonsense, frameshift, or splice-site variants that abolish a canonical splice-site [-2 or +2 bases from exon boundary]) and missense variants

Of the mothers who reported smoking in the three months leading up to pregnancy, 81.3% ( n = 565) tried to quit smoking once they became pregnant

Adopt healthy sleep habits: Establish a regular sleep schedule, create a relaxing bedtime routine, and make your sleep environment conducive to rest

It is thought that smoking may damage the cells which line blood vessels and these damaged cells cause the vessels to leak, allowing the toxic chemicals in cigarette smoke to damage the brain

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