21+ tobacco & vape Flum Pebble Classic Tobacco Lost Mary MT35K

3 December 2010

Currently, most AI-based systems exhibit deficiencies in generalizability and clinical applicability, especially when dealing with schizophrenia medical data that have significant differences in diagnostic criteria 99

Years ended 31 December 2025 2024 pence pence Diluted earnings per share 349.1 136.0 Effect of amortisation and impairment of goodwill, trademarks and similar intangibles 68.2 80.7 Effect of impairment charges in respect of the Group's head office 2.9 Effect of impairment charges in respect of the Group's operations in Cuba 1.6 Effect of settlement of historical litigation in relation to the Fox River (4.9) Effect of the changes in provision in relation to the Approved Plans in Canada and associated costs (23.7) 205.0 Effect of charges in respect of DOJ and OFAC investigations 0.2 Effect of impairment of held-for-sale assets and associated costs 5.5 Effect of Romania other taxes (0.7) 20.1 Effect of restructuring costs 1.8 Effect of other adjusting items in operating profit 5.1 5.3 Effect of adjusting items in net finance costs 4.9 (17.0) Effect of gains related to the partial divestment of shares held in ITC (40.8) (61.1) Tax associated with the partial divestment of shares held in ITC and hotels business demerger 1.6 1.6 Effect of associates adjusting items (15.5) (0.8) Effect of adjusting items in respect of deferred taxation (9.2) (12.0) Adjusting items in tax 4.5 4.9 Redemption of perpetual hybrid bond - difference in spot rates 1.3 Adjusted diluted earnings per share 352.1 362.5 Impact of translational foreign exchange 12.9 Adjusted diluted earnings per share translated at 2024 exchange rates 365.0 362.5 The presentation of headline earnings per share, as an alternative measure of earnings per share, is mandated under the JSE Listing Requirements

The CDC states unequivocally that using any commercial tobacco product is unsafe

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