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The injurious effect of smoking becomes more apparent when thyroid function is slightly compromised.[] Thus, smoking has been found to contribute toward development of overt hypothyroidism[] and subclinical hypothyroidism, as much as 10% in some studies,[] particularly in areas of iodine deficiency

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Between 1995 and 1998 Jean-Pierre Changeux received grants totalling 220,000 USD from the Council for Tobacco Research.[1] In the late 1990s he became a collaborator and advisor for Targacept, a pharmaceutical subsidiary of RJ Reynolds,[2] and in 2006/2007 he supervised and published studies funded by Philip Morris International.[3] The results of a small study with significant flaws are being blown out of proportion and peoples lives are potentially being put at risk as a result, said Professor Anna Gilmore, Director of the Tobacco Control Research Group at the University of Bath and Partner in STOP