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The cost of smoking-related disease is a significant cost burden on the Gross Domestic Product of the US economy

The law prohibits anyone under 21 years of age from possessing a nicotine product

During the lasering process the humidity needs to be kept at about 55%RH to prevent clogging of the suction holes in the holder

Synthetic nicotine is also found in dissolvable products, which are sold in the form of sticks, lozenges, strips or nicotine gum

This research was funded by the Key Project of China National Tobacco Corporation [110202201036(XJ-07)] and the Key Project of Sichuan Branch of China National Tobacco Corporation (SCYC202324, SCYC202127, and SCYC201913)