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Additives are important elements of tobacco products because they allow manufacturers to modify the sensory and pharmacological properties of tobacco products in a way that affects initiation and cessation (with additives that make the smoke less harsh or more pleasant to the user) or bioavailability and impact of nicotine (through changes in smoke pH or through additives such as menthol) (Box 1) [3],[4]

Toxicokinetic and genotoxicity study of NNK in male Sprague-Dawley rats following nose-only inhalation exposure, intraperitoneal injection, and oral gavage

What appears to be a procedural shift is in reality a major reset of how sin goods will be taxed in the long term

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Should be interpreted to mean safer