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Typical estimates suggest: 820 mg nicotine in raw tobacco per cigarette 12 mg nicotine absorbed by the smoker This difference occurs because some nicotine is lost during combustion and smoke dilution.According to Health Canada tobacco research, cigarette characteristics such as ignition properties and tobacco composition can influence smoke yield and nicotine exposure

Tobacco companies have seized the concept of harm reduction the proven public health approach of providing evidence-based lower harm alternatives for those who don't quit harmful substances as a proxy for a vision of a lightly regulated market of nicotine products that provides for continued and robust growth of nicotine as a commercial product

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