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The show based on the Barry Meier book Pain Killer: An Empire of Deceit and the Origin of Americas Opioid Epidemic and the Patrick Radden Keefe article The Family That Built an Empire of Pain in The New Yorker is the second prestige series, after Dopesick, to depict the opioid epidemic

For a show in which so little actually happens, its clear Matthew Weiner, the shows creator, is rushing to tie up loose ends, like Betty and Sallys fraught relationship, which has led to some soap-operatic plot twists

Estimates by the U.S

And then theres the anal-rape-death scene, an obvious nod to Se7en

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