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Legally, the minimum age to purchase tobacco in the U.S

By estimating the number of puffs per milliliter and the nicotine content per puff, users can determine their nicotine intake and compare it to smoking traditional cigarettes more accurately

Jessica Yingst, first author and researcher at the College of Medicine, said that previous studies of other electronic cigarettes with high liquid nicotine concentrations revealed that many delivered very little nicotine to the user

Additionally, tobacco use costs nearly $300 billion a year in direct health care and lost productivity

and adults with serious psychological distress