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The authors found no significant differences between the observed nicotine intakes and the expected intakes, suggesting that participants using low-nicotine cigarettes most likely had not increased the intensity of their puffs to obtain more nicotine

Fourth, smoking exposure is self-reported and may be under- or mis-reported especially across diverse sociocultural or regulatory environments thereby affecting the precision of smoking-attributable burden estimates

Reynolds succeeded in developing the technology, but never really succeeded in turning it into a transformative breakthrough, said Matthew Myers, the president of the Campaign for Tobacco-Free Kids in Washington, D.C

Avoid excessive or strenuous exercise that can cause stress to the body

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