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The answer is nicotine

Presence of Other Alkaloids: Some research indicates that e-vapor can contain nicotyrine at higher concentrations than cigarette smoke, which may inhibit enzymes that metabolize nicotine, potentially prolonging its effects and complicating direct equivalence calculations

Still, what really matters is how the game plays out

#1 on the list of causes of smoking cigarettes

In the UK, we are proud to be a standard bearer for a consumer-driven industry which has already helped millions of people across the world stop smoking, said Dan Marchant, a spokesman for the UK Vaping Industry Association