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That first cigarette of the day can put stress on multiple systems in your body. Smoking on an empty stomach may irritate the digestive system and increase inflammation. Nicotine raises heart rate Smoking Health Risks, Addiction, History Britannica The Story Of Your First Cigarette The Awl How Effective is Nicotine Replacement Therapy in : BMJ Most women focus on quitting for their lungs. But your skin is keeping a completely different scorecard and it started tallying the moment you lit your first cigarette. The aging happening

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