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in-vitro study that concentrations of protein glycation products (Amadori products, -amyloid, AGEs), glycooxidation products (dityrosine, kynurenine, N-formylkynurenine) and oxidation products (protein carbonyl groups, advanced oxidation protein products) decreased markedly in the presence of glycating agents (glucose, fructose, galactose, glyoxal and methylglyoxal) following the addition of propranolol ( FIGURE 3 6.2 Nebivolol Nebivolol has been the subject of research regarding its potential effect on oxidative stress and its implications for various health conditions

And it isn't just active smokers adding to the total

"Overview of the Family Smoking Prevention and Tobacco Control Act: Consumer Fact Sheet"

The product never hit the market and we dont know if a prototype has ever been made