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NHS figures for 2021 showed that 9% of 11 to 15 year old children used e-cigarettes, up from 6% in 2018

It also could spur a wave of consolidation in the tobacco business, shrink factories and workforces, and push prices for cigarettes higher even as smokers buy fewer of them

The mechanisms behind these associations suggest that oral bacteria and their metabolites can enter the bloodstream through oral epithelial barriers or via direct interactions with the respiratory and digestive systems, thereby influencing systemic health [33,34,35]

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