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Nicotine in tobacco can also cause an adrenaline rush, leaving someone feeling tired when it wears off

24 found that the overexpression of TERT in transgenic mice can improve the adaptability of the epithelial barrier, especially skin and intestinal tract, and lead to the delay of body aging, accompanied by the extension of the median life span, indicating that TERT has anti-aging activity in the mammalian body

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