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Nicotine was a factor in Christian Bale's extreme transformation for The Machinist, where he lost 62lbs or about a third of his bodyweight by surviving on a diet of an apple and black coffee a day and taking up smoking

[142] Acrylonitrile and ethylbenzene have been found in the e-cigarette vapor

Before Surgery, some hospitals require nicotine screening before surgery

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Results of lab-based studies, including some in animals, suggest that compounds called nitrosamines in e-cigarettes can damage DNA, according to The team reported that lung cells were less able to repair themselves after exposure to e-cigarette smoke