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The FTC alleged that Joe Camel was intended to introduce the next generation to cigarettes, rather than poach consumers from competing brands

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About half of cigarette smokers die of tobacco-related disease and lose on average 14 years of life.[9] Cigarette use by pregnant women has also been shown to cause birth defects, including low birth weight, fetal abnormalities, and premature birth

Specific compounds and mixtures which are most likely responsible for human disease have to be considered along with the route of administration (i.e