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An important implication of our study results is that the first-generation e-cigarettes many smokers first try [5] only deliver small amounts of nicotine, even after very intensive puffing (30 puffs over 10 minutes)

Metabolite: A substance produced when the body breaks down a compound, such as nicotine

Proponents of increasing the legal age beyond 18 said that if young potential smokers (or vapers) didnt regularly socialize with people old enough to legally purchase tobacco or vaping products, fewer teenagers would have access and become regular users