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However, the change from baseline did not differ significantly between treatment groups (-4.2 7.5 and -5.6 8.7 cigarettes per day for placebo and OROS-MPH respectively

There are two methods for vaping: DTL (Direct-to-Lung) and MTL (Mouth-to-Lung), depending on which type of device you have will mean you either hold the vapour in your mouth before opening your mouth and inhaling the vapour then exhale, or directly inhaling the vapour before exhaling

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