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Simultaneously, India must also explore pathways to support smokers who may benefit from relatively safer alternatives, requiring evidence-informed policy to protect population health in an evolving landscape of nicotine consumption

Going up in smoke

In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication

During these trials, all adverse events were recorded by the clinical investigators using terminology of their own choosing