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H2 2025 Further improvement in New Category contribution 1 , driven by Modern Oral and Vapour H2 weighted Group profit 3 delivery, driven by stabilising our performance in APMEA and the increasing realisation of Fit2Win savings through the year Confident in sustainably delivering our mid-term algorithm: 3-5% revenue, 4-6% APFO 3 and 5-8% adjusted diluted EPS 3 growth, with 2026 performance still expected at the lower end of these ranges Strong cash generation, with balanced capital allocation

Potential Risks and Side Effects of Combining Tirzepatide with Cannabis While direct pharmacological interactions may be minimal, combining tirzepatide with cannabis carries several indirect risks that warrant careful consideration

It shows that disruption feels more powerful when its rooted in legacy & DNA and the cigarette box testers are a stroke of genius in creating instant cultural buzz

Although biochemical assessments, including cotinine levels, have often been suggested to directly measure smoke exposure, they do not assess long-term smoking status

This allows oxygen levels to increase, reducing stress on the heart and other organs