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PKB/Akt phosphorylates and activates phosphodiesterase 3B, which degrades cAMP in adipocytes, releasing PKA from activation and decreasing lipolysis through a reduction in the phosphorylation-mediated activation of HSL and perilipin

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It also activates ERR and ERR

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These formulas contain bioactive compounds like flavonoids, terpenoids, alkaloids, curcumin, and cinnamaldehyde, which work synergistically to lower blood glucose levels and improve metabolic functions ( Figure 1 The glucose-lowering potential of TCM agents operates via multiple biochemical pathways, impacting both fasting and postprandial glycemic control