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Our results demonstrate that cytosolic p53 binds to Parkin and inhibits mitophagy by preventing Parkins translocation from the cytosol to the mitochondria, which decreases mitophagy activation and leads to hepatocyte apoptosis in HS-ALI

G., Olmstead, R

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Tobacco smoke contains more than 6,000 chemicals, of which around 100 harmful and potentially harmful constituents (HPHCs) have been classified by public health agencies as contributing to smoking-related disease

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