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A validated single-step saliva and serum sample extraction LC-MS/MS method for the analysis of nicotine, cotinine and 3-hydroxycotinine for clinical vaping studies

Reynolds Tobacco Co., the corporation that makes the wildly-popular Newport cigarettes, said Thursday

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[589] Section 1860D-14B(b)(5)(B)(ii) of the Act further states that for a Part D rebatable drug, the term line extension means, a new formulation of the drug, such as extended release formulation, but does not include an abuse-deterrent formulation of the drug (as determined by the Secretary), regardless of whether such abuse-deterrent formulation is an extended release formulation. This language is identical to the definition of line extension in section 1927(c)(2)(C) of the Act