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We selectively reexpressed 2 nAChRs in VTA dopamine or VTA -amino-butyric acid (GABA) neurons in 2/ mice to double-dissociate the aversive and rewarding conditioned responses to nicotine in nondependent mice, revealing that 2 nAChRs on VTA dopamine neurons mediate nicotines conditioned aversive effects, while 2 nAChRs on VTA GABA neurons mediate the conditioned rewarding effects in place-conditioning paradigms

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First Nations chief seeking a reversal of fur product ban on Etsy This is the fourth set of warnings mandated by Health Canada since 2000, aiming to reduce tobacco use to less than 5 per cent by 2035

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