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Moreover, some would argue (including myself) that increased ACE2 may in fact be protective, as ACE2 decreases the levels of angiotensin-2 which likely plays a significant role in the pathophysiology of ARDS. Some researchers have examined the limited evidence of smoking on COVID-19 risk and come to preliminary conclusions

Most of the respondents in both surveys 68 to 75 per cent had never smoked, while 17 to 22 per cent had experimented with cigarettes and around 10 per cent were already regular smokers, defined as smoking at least one cigarette every week

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Considering these notions, it is imperative to conduct further studies to examine the safety of e-cigarette smoking and the potential health hazards associated with it