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[33] Additionally, lung diseases (such as pneumonia, lung cancer, pulmonary embolism, and sarcoidosis) may play a role in certain people

COPD is primarily caused by smoking, but people can also get it from long-term exposure to dust, fumes, and chemicals

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The initial loss of tracheal mucosal cells followed by a hyperplastic response at the higher smoke exposure levels is consistent with initial apoptotic cell loss and subsequent cellular differentiation accompanying the reparative hyperplastic response

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