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The activation and/or upregulation of many xenobiotic metabolism enzymes is driven by exposure to chemicals that can serve as substrates

It is of the utmost importance to investigate further the possible long-term effects of daily e-cigarette use through studies that are funded independently of the e-cigarette industry. Dr Lundbck and his colleagues are continuing to investigate the effects of e-cigarettes on blood vessel and lung functions in humans, as well as carrying out studies in the lab of the effect of e-cigarette vapour and liquid on cell cultures.

Figures indicate that since the smoking ban has come into force, the prevalence of smokers has decreased, though not as much as expected

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