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Internationally, Canada was the first in 2001 to require pictorial health warnings

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Quebec tends to offer some of the more affordable cigarette prices in Canada, while Atlantic provinces and territories sit at the higher end

This work also has other important strengths over previous studies including the sample size, length of intervention, multiple toxicant exposure measures and control conditions. The question of whether an e-cigarettes nicotine delivery profile is predictive of its ability to reduce harm and promote behavior change among smokers remains highly relevant to policymakers, public health advocates, health care providers and smoking populations