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After adjusting for confounding variables, the researchers found that increasing levels of cotinine were associated with higher levels of total testosterone, until a certain inflection point, after which more cotinine was linked with lower testosterone

In other countries, RYO cigarette use has been shown to be consistently and significantly associated with low income.2123 Although it cannot be confirmed with cross-sectional analyses, the concurrent use of RYO cigarettes suggests that low-income smokers in Zambia may be substituting them for FM cigarettes, and this serves as a reminder that future policies should not be limited to only FM cigarettes

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