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Research has shown that the severity of nicotine withdrawal symptoms can vary depending on factors such as the duration and intensity of smoking, the number of cigarettes smoked per day, and individual susceptibility

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LDX, like all amphetamine stimulants, has direct appetite suppressant effects that may be therapeutically useful in BED, although long-term neuroadaptations in dopaminergic and noradrenergic systems caused by LDX may also be relevant, leading to improved regulation of eating behaviours, attentional processes and goal-directed behaviours