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12 Potential adverse effects and risk considerations of probiotic supplementation 12.1 Historical safety record and regulatory frameworks For centuries, the consumption of fermented foods containing live microorganisms has been associated with human health benefits, providing a strong historical foundation for their safety

Sudan SK, Sharma A, Vikramdeo KS, et al

[53] assessed GI (AEs) occurring after sc 2.4 mg semaglutide OW in adults with overweight or obesity using pooled data from the Semaglutide Treatment Effect in People With Obesity (STEP) 13 trials for participants randomized to 68 weeks of semaglutide 2.4 mg ( n = 2117) or placebo ( n = 1262)