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The phase Ib TROPION-Lung02 trial is a dose-escalation and -expansion study evaluating Dato-DXd (4 or 6 mg/kg) combined with pembrolizumab (doublet) with or without platinum agents (triplet therapy) in both previously untreated and pre-treated patients with metastatic NSCLC without actionable genomic alterations

We initially induced oxidative stress through intraperitoneal injection of DQ, leading to a reduction in serum antioxidant capacity

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[DOI] [PubMed] [Google Scholar] 20.Fabender K., Mielke O., Bertsch T., Hennerici M