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On the one hand, oxidative stress can result in cardiac fibrosis by stimulating the proliferation of cardiac fibroblasts which is responsible for extracellular matrix remodeling [100]

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Hypertension was defined as ever told you had high blood pressure or currently taking prescribed medication for high blood pressure (HBP). Diabetes was defined as doctor told you have diabetes, two-hour glucose oral glucose tolerance test (OGTT) (mmol/L) 11.1, or fasting glucose (mmol/L) 7.0. Prediabetes was defined as ever told you have prediabetes, two-hour glucose (OGTT) (mmol/L) = 7.811.1, or fasting glucose (mmol/L) = 6.16.9. Smoking status was classified as non-smokers (never smoked or quit smoking for more than 1 year) and current smokers (currently smoking, smoked more than 1 day in the past 30 days, wake up to smoke, or smoke more than two cigarettes per day after quitting)