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Cardiovasc Toxicol 15:107116 Asano H, Horinouchi T, Mai Y, Sawada O, Fujii S, Nishiya T, Minami M, Katayama T, Iwanaga T, Terada K, Miwa S (2012) Nicotine- and Tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase

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The other elements seem to have a smoothing out effect

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