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Contamination from external sources or the upper airway can also interfere with analysis, leading to inaccurate data interpretation [133, 134]

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The goal is to understand what parts of the brain should be stimulated and what processes change from stimulation, and if this therapy can be used to treat other substance use disorders

John Britton, director of the UK Centre for Tobacco and Alcohol Studies at the University of Nottingham said "This significant year-on-year fall indicates that something in UK tobacco control policy is working, and successful quitting through substitution with e-cigarettes is one likely major contributor." The safety of e-cigarettes has been questioned