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Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention Nature Reviews Cancer Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Quitting Smoking Cigarette smoke contains thousands of chemicals, many of which are toxic and harmful to the human body. Here's a detailed breakdown of some of the most dangerous constituents and their effects: 1. Commonly Used Drugs Tobacco Nicotine StoryMD

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