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That first cigarette of the day can put stress on multiple systems in your body. Smoking on an empty stomach may irritate the digestive system and increase inflammation. Nicotine raises heart rate What Happens to Your Body, When You Take a Puff of a Cigarette? Keck Medicine of USC Lighting up your first cigarette on an empty stomach may place extra stress on several major organs. Smoking can irritate the stomach lining, potentially increasing the risk of inflammation and ulcers, while Nicorette 2 mg Fruit Chill Nicotine Gum Hannaford My First Cigarette Story

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