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In 1560, intrigued by the medicinal properties attributed to the plant, Nicot sent tobacco seeds and leaves to the French court, where it was initially lauded as a "wonder drug." While Nicot's introduction of tobacco primarily focused on its potential medicinal uses, the ornamental value of Nicotiana alata would later become prized in gardens

As a result, breathing becomes more difficult

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Additionally, studies have shown decreasing vitamin C levels as the number of cigarettes smoked per day increases

It is not advisable to directly remove the amount of CO that is breathed since this might alter the gradient of CO concentration over the alveolar membranes and perhaps in the airways by Chatkin et al