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He called it "a custome lathsome to the eye, hateful to the nose, harmeful to the braine, dangerous to the lungs, and the black stinking fume thereof, nearest resembling the horrible Stigian smoke of the pit that is bottomlesse" ( Counterblaste to Tobacco , 1604)

Front Oncol 5:196 Satelli A, Li S (2011) Vimentin in cancer and its potential as a molecular target for cancer therapy

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Since nicotine may produce a number of reactive oxygen species, one theory contends that decrease in sperm count is caused by nicotine-mediated oxidative stress [31]

The biggest challenge was getting the actors to focus on the splitter instead of one of the camera lenses