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Reutens AT, Jandeleit-Dahm K, Thomas M et al (2019) A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: protocol and statistical considerations

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In the clinical trial, compared to women in the control group, women receiving NAC had significantly lower average uFSH dosage and duration ( p 0.05)

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TM3 cells were harvested after treatment, stained with Annexin V-FITC and PI reagent, and incubated in the dark for 15 minutes