CA-Cy3 protac Nature Chemistry

Nature Chemistry

75 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

TMX-4100 can be used for the research of multiple myeloma

TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader

CA-Cy3 protac Nature ChemistryHaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA Cy3 is a HaloTag ligand with Cyanine3 dye. Cy3 (Cyanine 3, 550Ex 570Em) is known for