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10.1002/ptr.7794 66 GhodsiaH.RahimibH

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This activation triggers a cascade of pathological processes, including intracellular ion homeostasis collapse, energy metabolism dysregulation, oxidative stress, and inflammatory responses, ultimately resulting in apoptosis and electrophysiological dysfunction of cardiomyocytes and neurons

The effects on EPSC frequency were associated with respective increases or decreases in intracellular glutamate

Depletion of DGAT2 or PLIN2 results in reduced lipid droplet formation, which is correlated with increased pro-apoptotic signaling, heightened follicular atresia, and decreased ovulated egg numbers [209, 210]