Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg PEG linkers enhance water solubility

PEG linkers enhance water solubility and provide spatial separation to minimize steric hindrance during binding interactions

Angewandte Chemie - International Edition

Product Name Thalidomide-C4-OH Synonyms Thalidomide-4'-C4-OH CAS Number n/a Related CAS Molecular Formula C17H18N2O5 Molecular Weight 330

Product Name Thalidomide-propargyl-O-C2-amine HCl Synonyms Thalidomide-4'-propargyl-O-C2-amine HCl CAS Number n/a Related CAS Molecular Formula C18H18ClN3O5 Molecular Weight 391

Product Name Pomalidomide-5'-PEG3-C2-amine HCl Synonyms CAS Number n/a Related CAS 1957236-37-1 (free base) Molecular Formula C21H29ClN4O7 Molecular Weight 484

Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg PEG linkers enhance water solubilitySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase