Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan adc Product Name Lenalidomide-CO-C3-alkyne Synonyms Lenalidomide-4'-CO-C3-alkyne

Product Name Lenalidomide-CO-C3-alkyne Synonyms Lenalidomide-4'-CO-C3-alkyne CAS Number 2408797-65-7 Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353

Product Name: Cy3 carboxylic acid monosulfo Synonyms: Cy3 carboxylic acid

378 SMILES O=C(CCCC#C)NC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name 1-Chloro-4-(methoxy-d3)naphthalene Synonyms CAS Number n/a Related CAS Molecular Formula C11H9ClO Molecular Weight 195

6 SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCC(O)=O)[C@@]1([H])NC(=O)N2 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan adc Product Name Lenalidomide-CO-C3-alkyne Synonyms Lenalidomide-4'-CO-C3-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is