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Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer

Non-Alcoholic Fatty Liver Disease (NAFLD) Fat accumulation in the liver creates: Oxidative stress Inflammatory signaling Insulin resistance GGT often rises early in NAFLD, sometimes before ALT becomes abnormal

PLoS Med 10 , e1001462 (2013)

As previously mentioned, in the eighth step of the pentose phosphate pathway, transketolase catalyzes the synthesis of fructose 6-phosphate and glyceraldehyde 3-phosphate from erythrose 4-phosphate and xylulose 5-phosphate, linking the activities of transaldolase and transketolase in the non-oxidative phase of the pathway

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