DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP deuterium-labeled-carboxylic ester Product Name Thalidomide-O-acetamido-C3-acid Synonyms Thalidomide-4'-O-acetamido-C3-acid

Product Name Thalidomide-O-acetamido-C3-acid Synonyms Thalidomide-4'-O-acetamido-C3-acid CAS Number 2308035-51-8 Related CAS Molecular Formula C19H19N3O8 Molecular Weight 417

NCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

dCeMM2 (Compound 2) is a glue degrader

NCCOCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

031 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP deuterium-labeled-carboxylic ester Product Name Thalidomide-O-acetamido-C3-acid Synonyms Thalidomide-4'-O-acetamido-C3-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further