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Paris saponin VII reverses chemoresistance in breast MCF-7/ADR cells

10.1007/s13760-021-01753-8 90 NakamuraR.KuriharaM.OgawaN.KitamuraA.YamakawaI.BambaS.et al

Initially, a fragment of 35 kDa, spanning the complete ligand binding domain and part of the hinge region, is protected from digestion by the ligand

Ingredients: De-ionized Water, Vegetable Glycerin, Malic Acid, Citric Acid, Natural Fruit Extracts and Flavors, Potassium Sorbate (as preservative), Lemon (Citrus limon) Oil Serving Size: 1 Tablespoon Servings Per Container: 63 Amount Per Serving: Calories 15 Total Carbohydrate 4 g Vitamin B-6 (from Pyridoxine HCl) 2 mg Pantothenic Acid(from D-Calcium Pantothenate) 10 mg L-Carnitine (Carnipure) (Free-Form Base) 1g Stevia Extract (Leaf) 16 mg Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients

Gabapentin/Pregabalin The gabapentinoids gabapentin (Neurontin) and pregabalin (Lyrica) have been suggested as potential treatments for CIPN due to their ability to treat peripheral nerve pain, although evidence for benefit in CIPN is inconsistent (Davis 2022