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Although several studies have shown positive effects of glutamine supplementation on metabolic variables in diabetes mellitus, there is no systematic review that summarizes the results of these studies

It creates an environment where we have legalized snake oil, says Pieter Cohen, an internal medicine physician at Cambridge Health Alliance in Massachusetts who studies supplement safety

Cardiovascular manifestations include peripheral vasodilation, biventricular failure, and edema

Its particularly well-suited for patients who do not tolerate or respond well to alternatives like naltrexone or disulfiram